Role of mean corpuscular volume in alcohol use disorders


  • Dr. Raja M Consultant Physician and Diabetologist, CM Speciality Hospital, Namakkal.


Alcohol, AUDIT, Mean Corpuscular Volume, Alcohol use disorder, Macrocytosis


Objective: To evaluate the usefulness of mean corpuscular volume to identify alcohol use disorder in comparison with AUDIT (Alcohol Use Disorders Identification Test) screening test.  Materials & Methods: This is a cross sectional study and it was conducted at the Institute of Internal Medicine, Madras Medical College & Rajiv Gandhi Government General Hospital, Chennai for a period of six months from June 2013 to November 2013. Qualitative variables are analysed by chi-square test. The quantitative data in this study were analysed using independent sample t test. Results: Total number of participants in this study was 100 in number who were found to having alcoholic disorders.  An analysis of these group of people, macrocytosis was noted in 61% and the remaining 39% had normal mean corpuscular volume. In our study, the prevalence of macrocytosis in patients with AUD is 61% with p value of 0.028. Conclusion: Diagnosing alcohol injection after development of alcohol dependence or alcohol related problems has no value in the management.  A combined use of AUDIT and cost-effective investigations like mean corpuscular volume.  We can diagnose the problem earlier and we can prevent the complications. Patients with macrocytosis without anemia should be evaluated for alcohol abuse.


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How to Cite

M, R. (2022). Role of mean corpuscular volume in alcohol use disorders. The Journal of Medicine and Science, 1(03), 23–33. Retrieved from



Research article