A case report of anterior mediastinal mass and a literature review


  • Dr. Baskar P Junior Resident, Department of General medicine, Coimbatore Medical College and Hospital, Coimbatore, Tamil Nadu, India.
  • Dr. Alagu Thiyagarajan A Senior Assistant Professor, Department of General Medicine, Coimbatore Medical College and Hospital, Coimbatore, Tamil Nadu, India.


Anterior mediastinum, Mediastinal Mass, seminoma, chemotherapy, radiotherapy, surgical resection, Computed Tomography


Herein authors presents a case of a 24 year old male presented with dry cough and facial puffiness for 6 months, breathlessness on exertion, dysphagia, PND, loss of weight and loss of appetite for 2 months. Chest X-ray and CE-CT showed anterior mediastinal mass. On further immunohistochemistry, it was found to be a germ cell tumour, prabably mediastinal seminoma. The case was then treated with bleomycin, etoposide, cisplatin regimen of chemotherapy and followed by radiation for residual lesion. Patient improved well and is in regular follow up.



Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest. 2005 Oct;128(4):2893-909.

Juanpere S, Cañete N, Ortuño P, Martínez S, Sanchez G, Bernado L. A diagnostic approach to the mediastinal masses. Insights Imaging. 2013 Feb;4(1):29-52.

Chen X, Xu H, Ni Y, Sun K, Li W. Complete excision of a giant thyroid goiter in posterior mediastinum. J Cardiothorac Surg. 2013 Nov 07;8:207.

Jain N, Chauhan U, Puri SK, Agrawal S, Garg L. Fibrosing mediastinitis: when to suspect and how to evaluate? BJR Case Rep. 2016;2(1):20150274.

Carter BW, Marom EM, Detterbeck FC. Approaching the patient with an anterior mediastinal mass: a guide for clinicians. J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S102-9.

Aroor AR, Prakasha S R, Seshadri S, S T, Raghuraj U. A study of clinical characteristicsof mediastinal mass. J Clin Diagn Res. 2014 Feb;8(2):77-80.

Friedman T, Quencer KB, Kishore SA, Winokur RS, Madoff DC. Malignant Venous Obstruction: Superior Vena Cava Syndrome and Beyond. Semin Intervent Radiol. 2017 Dec;34(4):398-408.

Knyazer B, Smolar J, Lazar I, Rosenberg E, Tsumi E, Lifshitz T, Levy J. Iatrogenic Horner Syndrome: Etiology, Diagnosis and Outcomes. Isr Med Assoc J. 2017 Jan;19(1):34-38 .

Gilhus NE. Myasthenia Gravis. N Engl J Med. 2016 Dec 29;375(26):2570-2581 .

Nagasaka T, Nakashima N, Nunome H. Needle tract implantation of thymoma after transthoracic needle biopsy. J Clin Pathol. 1993 Mar;46(3):278-9.



How to Cite

P, B., & A, A. thiyagarajan. (2023). A case report of anterior mediastinal mass and a literature review. The Journal of Medicine and Science, 2(03), 51–53. Retrieved from https://tjms.in/index.php/tjms/article/view/33



Case reports